Convergence overclaimed by 74%. Despite high internal agreement (82%) across 8 scientific worldviews, only 8% of specific mechanistic claims are grounded in published peer-reviewed evidence.
Top Supported Claims
No strongly supported claims found
Contradicted / Overclaimed
C001: Multiple worldviews converge on neuroplasticity and circuit remodeling as the primary underlying mechanism (delta: -90%)
C002: Cross-disciplinary convergence with 2022-2025 evidence identifies TrkB-mediated neuroplasticity as ground truth (delta: -62%)
Key 2022-2025 Evidence Incorporated
Johansen 2023 — First human PET evidence of synaptic density change (healthy volunteers, replication needed)
Casarotto 2021 / Kot 2024 — TrkB binding confirmed (Brunello 2024 calls this "rethinking," not settled)
Nichols 2023 — SSRIs accumulate ~180x in cell membranes (non-specific to all membrane proteins)